Kotzebue
- County:
- Northwest Arctic Borough
- County Seat:
- Yes
- Area (mi²):
- 24.409
- State:
- Alaska
Kotzebue is a city located in Northwest Arctic Borough, Alaska. Kotzebue has a 2026 population of 2,889. It is also the county seat of Northwest Arctic Borough. Kotzebue is currently declining at a rate of -1.67% annually and its population has decreased by -6.81% since the most recent census, which recorded a population of 3,100 in 2020.