San Bruno
- County:
- San Mateo County
- County Seat:
- No
- Area (mi²):
- 5.489
- State:
- California
San Bruno is a city located in San Mateo County, California. San Bruno has a 2026 population of 42,035. San Bruno is currently growing at a rate of 0.74% annually but its population has decreased by -3.92% since the most recent census, which recorded a population of 43,750 in 2020.