Chillicothe is a city located in Ohio. With a 2020 population of 21,638, it is the 76th largest city in Ohio and the 1737th largest city in the United States. Chillicothe is currently declining at a rate of -0.14% annually and its population has decreased by -1.20% since the most recent census, which recorded a population of 21,901 in 2010. Chillicothe reached it's highest population of 24,957 in 1960. Spanning over 11 miles, Chillicothe has a population density of 2,076 people per square mile.
The average household income in Chillicothe is $58,589 with a poverty rate of 18.55%. The median rental costs in recent years comes to $743 per month, and the median house value is $112,400. The median age in Chillicothe is 41.6 years, 39.8 years for males, and 43.8 years for females. For every 100 females there are 95.5 males.