Clio is a city located in Marlboro County South Carolina. With a 2020 population of 644, it is the 183rd largest city in South Carolina and the 12226th largest city in the United States . Clio is currently declining at a rate of -1.08% annually and its population has decreased by -11.29% since the most recent census, which recorded a population of 726 in 2010. Clio reached it's highest population of in . Spanning over 1 miles, Clio has a population density of 752 people per square mile.
The average household income in Clio is $44,292 with a poverty rate of 38.25%. The median rental costs in recent years comes to $575 per month, and the median house value is $56,300. The median age in Clio is 35.8 years, 36.3 years for males, and 33.3 years for females.