Thompsonville
- County:
- Franklin County
- County Seat:
- No
- Area (mi²):
- 2.031
- State:
- Illinois
Thompsonville is a village located in Franklin County, Illinois. Thompsonville has a 2026 population of 479. Thompsonville is currently declining at a rate of -0.21% annually and its population has decreased by -1.24% since the most recent census, which recorded a population of 485 in 2020.