29 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| Evansville | Vanderburgh County | 114,899 |
| Elkhart | Elkhart County | 53,640 |
| East Chicago | Lake County | 25,624 |
| Elwood | Madison County | 8,517 |
| Ellettsville | Monroe County | 6,873 |
| Edinburgh | Johnson County | 4,488 |
| Edgewood | Madison County | 2,081 |
| Eaton | Delaware County | 1,594 |
| Enchanted Hills | 1,345 | |
| Everton | 739 | |
| English | Crawford County | 688 |
| Elberfeld | Warrick County | 675 |
| Elnora | Daviess County | 628 |
| Etna Green | Kosciusko County | 580 |
| Elizabethtown | Bartholomew County | 419 |
| Earl Park | Benton County | 365 |
| Edwardsport | Knox County | 279 |
| East Germantown | Henry County | 258 |
| Eminence | Morgan County | 205 |
| Elizabeth | Harrison County | 201 |
| Eugene | 200 | |
| East Oolitic | 175 | |
| Eden | 154 | |
| Economy | Wayne County | 147 |
| East Enterprise | Switzerland County | 119 |
| Eckerty | Crawford County | 70 |
| Elizaville | 45 | |
| Elrod | 14 | |
| Emison | Knox County | 4 |