
Holy Cross
- County:
- Dubuque County
- County Seat:
- No
- Area (mi²):
- 0.328
- State:
- Iowa
Holy Cross is a city located in Dubuque County, Iowa. Holy Cross has a 2025 population of 340. Holy Cross is currently declining at a rate of -1.16% annually and its population has decreased by -5.56% since the most recent census, which recorded a population of 360 in 2020.
The average household income in Holy Cross is $79,432 with a poverty rate of 3.03%. The median age in Holy Cross is 48.7 years: 48.6 years for males, and 49 years for females.