Osceola
- County:
- Clarke County
- County Seat:
- Yes
- Area (mi²):
- 7.967
- State:
- Iowa
Osceola is a city located in Clarke County, Iowa. Osceola has a 2026 population of 5,585. It is also the county seat of Clarke County. Osceola is currently declining at a rate of -0.13% annually but its population has increased by 3.06% since the most recent census, which recorded a population of 5,419 in 2020.