Salyersville is a city located in Magoffin County, Kentucky. Salyersville has a 2026 population of 1,499. It is also the county seat of Magoffin County. Salyersville is currently declining at a rate of -0.33% annually and its population has decreased by -5.43% since the most recent census, which recorded a population of 1,585 in 2020.