Columbus
- County:
- Lowndes County
- County Seat:
- Yes
- Area (mi²):
- 25.049
- State:
- Mississippi
Columbus is a city located in Lowndes County, Mississippi. Columbus has a 2026 population of 22,820. It is also the county seat of Lowndes County. Columbus is currently declining at a rate of -0.86% annually and its population has decreased by -4.9% since the most recent census, which recorded a population of 23,995 in 2020.