
Caruthersville
- County:
- Pemiscot County
- County Seat:
- Yes
- Area (mi²):
- 5.158
- State:
- Missouri
Caruthersville is a city located in Pemiscot County, Missouri. Caruthersville has a 2025 population of 5,022. It is also the county seat of .Caruthersville is currently declining at a rate of -2.01% annually and its population has decreased by -9.28% since the most recent census, which recorded a population of 5,536 in 2020.
The average household income in Caruthersville is $62,669 with a poverty rate of 26.06%. The median age in Caruthersville is 36.2 years: 36.1 years for males, and 36.5 years for females.