Perryville
- County:
- Perry County
- County Seat:
- Yes
- Area (mi²):
- 8.16
- State:
- Missouri
Perryville is a city located in Perry County, Missouri. Perryville has a 2026 population of 8,554. It is also the county seat of Perry County. Perryville is currently growing at a rate of 0.55% annually but its population has decreased by -0.07% since the most recent census, which recorded a population of 8,560 in 2020.