Poplar Bluff
- County:
- Butler County
- County Seat:
- Yes
- Area (mi²):
- 13.503
- State:
- Missouri
Poplar Bluff is a city located in Butler County, Missouri. Poplar Bluff has a 2026 population of 16,177. It is also the county seat of Butler County. Poplar Bluff is currently declining at a rate of -0.16% annually and its population has decreased by -0.65% since the most recent census, which recorded a population of 16,283 in 2020.