St. James
- County:
- Phelps County
- County Seat:
- No
- Area (mi²):
- 4.272
- State:
- Missouri
St. James is a city located in Phelps County, Missouri. St. James has a 2026 population of 3,932. St. James is currently growing at a rate of 0.33% annually and its population has increased by 0.49% since the most recent census, which recorded a population of 3,913 in 2020.