Waynesville
- County:
- Pulaski County
- County Seat:
- Yes
- Area (mi²):
- 7.153
- State:
- Missouri
Waynesville is a city located in Pulaski County, Missouri. Waynesville has a 2026 population of 5,493. It is also the county seat of Pulaski County. Waynesville is currently growing at a rate of 0.62% annually and its population has increased by 1.2% since the most recent census, which recorded a population of 5,428 in 2020.