Wilkesville
- County:
- Vinton County
- County Seat:
- No
- Area (mi²):
- 0.259
- State:
- Ohio
Wilkesville is a village located in Vinton County, Ohio. Wilkesville has a 2025 population of 109 . Wilkesville is currently declining at a rate of 0% annually and its population has decreased by -2.68% since the most recent census, which recorded a population of 112 in 2020.
The median age in Wilkesville is 41.9 years: 33.3 years for males, and 42.5 years for females. For every 100 females there are 105.0 males.