Wayne
- County:
- McClain County
- County Seat:
- No
- Area (mi²):
- 0.38
- State:
- Oklahoma
Wayne is a town located in McClain County, Oklahoma. Wayne has a 2026 population of 670. Wayne is currently growing at a rate of 1.36% annually and its population has increased by 7.54% since the most recent census, which recorded a population of 623 in 2020.