14 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| York | York County | 45,355 |
| York | York County | 31,850 |
| Yeadon | Delaware County | 12,497 |
| Youngwood | Westmoreland County | 2,890 |
| Yardley | Bucks County | 2,588 |
| Young | Indiana County | 1,683 |
| Young | Jefferson County | 1,655 |
| Youngsville | Warren County | 1,647 |
| Yoe | York County | 1,064 |
| York Springs | Adams County | 708 |
| York Haven | York County | 696 |
| Yatesville | Luzerne County | 649 |
| Youngstown | Westmoreland County | 242 |
| Yorkana | York County | 238 |