Ohiopyle
- County:
- Fayette County
- County Seat:
- No
- Area (mi²):
- 0.418
- State:
- Pennsylvania
Ohiopyle is a borough located in Fayette County, Pennsylvania. Ohiopyle has a 2026 population of 36. Ohiopyle is currently declining at a rate of 0% annually and its population has decreased by -5.26% since the most recent census, which recorded a population of 38 in 2020.