14 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| Dakota Dunes | Union County | 4,996 |
| Dell Rapids | Minnehaha County | 3,783 |
| Deadwood | Lawrence County | 1,469 |
| De Smet | Kingsbury County | 1,034 |
| Dupree | Ziebach County | 466 |
| Doland | Spink County | 185 |
| Dimock | Hutchinson County | 156 |
| Delmont | Douglas County | 152 |
| Dallas | Gregory County | 83 |
| Dante | Charles Mix County | 67 |
| Davis | Turner County | 56 |
| Draper | Jones County | 38 |
| Dolton | Hutchinson County | 36 |
| Dudley | Sioux County | 9 |