Colome
- County:
- Tripp County
- County Seat:
- No
- Area (mi²):
- 0.282
- State:
- South Dakota
Colome is a city located in Tripp County, South Dakota. Colome has a 2026 population of 337. Colome is currently growing at a rate of 2.12% annually and its population has increased by 2.43% since the most recent census, which recorded a population of 329 in 2020.