Mission Hill
- County:
- Yankton County
- County Seat:
- No
- Area (mi²):
- 0.328
- State:
- South Dakota
Mission Hill is a town located in Yankton County, South Dakota. Mission Hill has a 2026 population of 182. Mission Hill is currently declining at a rate of -1.62% annually and its population has decreased by -4.71% since the most recent census, which recorded a population of 191 in 2020.