Pukwana
- County:
- Brule County
- County Seat:
- No
- Area (mi²):
- 0.767
- State:
- South Dakota
Pukwana is a town located in Brule County, South Dakota. Pukwana has a 2026 population of 236. Pukwana is currently declining at a rate of -0.84% annually but its population has increased by 1.29% since the most recent census, which recorded a population of 233 in 2020.