Nacogdoches is a city located in Nacogdoches County, Texas. Nacogdoches has a 2026 population of 32,381. It is also the county seat of Nacogdoches County. Nacogdoches is currently declining at a rate of -0.1% annually but its population has increased by 0.83% since the most recent census, which recorded a population of 32,115 in 2020.