| City | County | 2026 Pop. ↓ |
|---|---|---|
| South Charleston | Kanawha County | 12,904 |
| St. Albans | Kanawha County | 10,078 |
| Summersville | Nicholas County | 3,270 |
| Shinnston | Harrison County | 2,227 |
| Spencer | Roane County | 1,871 |
| Star City | Monongalia County | 1,801 |
| Stonewood | Harrison County | 1,728 |
| St. Marys | Pleasants County | 1,724 |
| Salem | Harrison County | 1,557 |
| Shepherdstown | Jefferson County | 1,521 |
| Sistersville | Tyler County | 1,299 |
| Sophia | Raleigh County | 1,063 |
| Sutton | Braxton County | 806 |
| Smithers | Fayette County | 683 |
| Sand Fork | Gilmer County | 165 |
| Sylvester | Boone County | 145 |
| Smithfield | Wetzel County | 95 |