Kewaunee is a city located in Kewaunee County, Wisconsin. Kewaunee has a 2026 population of 2,808. It is also the county seat of Kewaunee County. Kewaunee is currently declining at a rate of -0.32% annually and its population has decreased by -0.5% since the most recent census, which recorded a population of 2,822 in 2020.