La Crosse
- County:
- La Crosse County
- County Seat:
- Yes
- Area (mi²):
- 21.711
- State:
- Wisconsin
La Crosse is a city located in La Crosse County, Wisconsin. La Crosse has a 2026 population of 51,049. It is also the county seat of La Crosse County. La Crosse is currently declining at a rate of -0.46% annually and its population has decreased by -3.06% since the most recent census, which recorded a population of 52,660 in 2020.