
Holmes County
- State:
- Mississippi
- County Seat:
- Lexington
Holmes County's estimated 2025 population is 15,109 with a growth rate of -2.16% in the past year according to the most recent United States census data. Holmes County is the 56th largest county in Mississippi. The 2010 population was 19,406 and has seen a growth of -22.14% since that time.