
Madison County
- State:
- Missouri
- County Seat:
- Fredericktown
Madison County's estimated 2025 population is 12,580 with a growth rate of -0.47% in the past year according to the most recent United States census data. Madison County is the 75th largest county in Missouri. The 2010 population was 12,197 and has seen a growth of 3.14% since that time.