Santa Ana
- County:
- Orange County
- County Seat:
- Yes
- Area (mi²):
- 27.376
- State:
- California
Santa Ana is a city located in Orange County, California. Santa Ana has a 2026 population of 316,184. It is also the county seat of Orange County. Santa Ana is currently growing at a rate of 1.13% annually and its population has increased by 1.59% since the most recent census, which recorded a population of 311,226 in 2020.