Carlisle is a city located in Union County South Carolina. With a 2020 population of 410, it is the 202nd largest city in South Carolina and the 14172nd largest city in the United States . Carlisle is currently declining at a rate of -0.24% annually and its population has decreased by -5.96% since the most recent census, which recorded a population of 436 in 2010. Carlisle reached it's highest population of in . Spanning over 1 miles, Carlisle has a population density of 290 people per square mile.
The average household income in Carlisle is $47,585 with a poverty rate of 33.68%. The median rental costs in recent years comes to $763 per month, and the median house value is $48,700. The median age in Carlisle is 44.7 years, 32 years for males, and 48 years for females.