St. Rose
- County:
- Clinton County
- County Seat:
- No
- Area (mi²):
- 0.591
- State:
- Illinois
St. Rose is a village located in Clinton County, Illinois. St. Rose has a 2026 population of 466. St. Rose is currently growing at a rate of 0.65% annually and its population has increased by 1.53% since the most recent census, which recorded a population of 459 in 2020.