22 cities
| City | Parish | 2025 Pop. ↓ |
|---|---|---|
| Destrehan | St. Charles Parish | 12,188 |
| DeRidder | Beauregard Parish | 9,427 |
| Denham Springs | Livingston Parish | 9,324 |
| Donaldsonville | Ascension Parish | 7,004 |
| DeQuincy | Calcasieu Parish | 2,808 |
| Delhi | Richland Parish | 2,511 |
| Des Allemands | St. Charles Parish | 2,299 |
| Delcambre | Vermilion Parish | 1,765 |
| Duson | Lafayette Parish | 1,340 |
| Deville | Rapides Parish | 913 |
| Dubach | Lincoln Parish | 901 |
| Dulac | Terrebonne Parish | 689 |
| Doyline | Webster Parish | 643 |
| Dry Prong | Grant Parish | 441 |
| Dodson | Winn Parish | 292 |
| Dixie Inn | Bienville Parish | 274 |
| Dubberly | Webster Parish | 235 |
| Delta | Madison Parish | 210 |
| Darrow | Ascension Parish | 171 |
| Dorseyville | Iberville Parish | 150 |
| Delacroix | Plaquemines Parish | 145 |
| Downsville | Union Parish | 111 |