16 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| Falmouth | Cumberland County | 12,925 |
| Freeport | Cumberland County | 8,935 |
| Farmington | Franklin County | 8,239 |
| Fairfield | Somerset County | 6,534 |
| Fort Kent | Aroostook County | 4,134 |
| Fryeburg | Oxford County | 3,582 |
| Fort Fairfield | Aroostook County | 3,270 |
| Farmingdale | Kennebec County | 3,032 |
| Franklin | Hancock County | 1,667 |
| Fayette | Kennebec County | 1,275 |
| Frankfort | Waldo County | 1,243 |
| Friendship | Knox County | 1,151 |
| Frenchville | Aroostook County | 1,022 |
| Freedom | Waldo County | 743 |
| Frenchboro | Hancock County | 30 |
| Frye Island | Cumberland County | 30 |