16 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| Falmouth | Cumberland County | 12,898 |
| Freeport | Cumberland County | 8,771 |
| Farmington | Franklin County | 8,589 |
| Fairfield | Somerset County | 6,540 |
| Fort Kent | Aroostook County | 4,242 |
| Fryeburg | Oxford County | 3,617 |
| Fort Fairfield | Aroostook County | 3,356 |
| Farmingdale | Kennebec County | 3,018 |
| Franklin | Hancock County | 1,637 |
| Fayette | Kennebec County | 1,283 |
| Frankfort | Waldo County | 1,277 |
| Friendship | Knox County | 1,131 |
| Frenchville | Aroostook County | 1,044 |
| Freedom | Waldo County | 728 |
| Frenchboro | Hancock County | 30 |
| Frye Island | Cumberland County | 29 |