9 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| Eugene | Lane County | 178,873 |
| Eagle Point | Jackson County | 9,834 |
| Estacada | Clackamas County | 5,854 |
| Eagle Crest | Crook County | 3,419 |
| Enterprise | Wallowa County | 2,091 |
| Elgin | Union County | 1,689 |
| Echo | Umatilla County | 624 |
| Elmira | Lane County | 510 |
| Elkton | Douglas County | 187 |