
O'Brien
- County:
- Josephine County
- County Seat:
- No
- Area (mi²):
- 5.221
- State:
- Oregon
O'Brien is a CDP located in Josephine County, Oregon. O'Brien has a 2025 population of 648. O'Brien is currently growing at a rate of 1.57% annually and its population has increased by 1.41% since the most recent census, which recorded a population of 639 in 2020.
The average household income in O'Brien is $40,389 with a poverty rate of 7.2%. The median age in O'Brien is 70.1 years: 70.1 years for males, and 68.6 years for females.