Jackson Center
- County:
- Mercer County
- County Seat:
- No
- Area (mi²):
- 1.138
- State:
- Pennsylvania
Jackson Center is a borough located in Mercer County, Pennsylvania. Jackson Center has a 2026 population of 186. Jackson Center is currently declining at a rate of -0.53% annually and its population has decreased by -3.13% since the most recent census, which recorded a population of 192 in 2020.