8 cities
| City | County | 2026 Pop. ↓ |
|---|---|---|
| Irmo | Richland County | 12,383 |
| Isle of Palms | Charleston County | 4,391 |
| India Hook | York County | 3,902 |
| Inman | Spartanburg County | 3,531 |
| Irwin | Lancaster County | 1,892 |
| Iva | Anderson County | 1,222 |
| Inman Mills | Spartanburg County | 860 |
| Islandton | Colleton County | 66 |