Isabel
- County:
- Dewey County
- County Seat:
- No
- Area (mi²):
- 0.845
- State:
- South Dakota
Isabel is a town located in Dewey County, South Dakota. Isabel has a 2026 population of 155. Isabel is currently growing at a rate of 6.16% annually and its population has increased by 6.16% since the most recent census, which recorded a population of 146 in 2020.