18 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| East Ridge | Catoosa County | 21,910 |
| Elizabethton | Carter County | 14,444 |
| Erwin | Unicoi County | 6,008 |
| Eagleton Village | Blount County | 5,397 |
| Etowah | McMinn County | 3,777 |
| Estill Springs | Franklin County | 2,697 |
| East Cleveland | Bradley County | 2,281 |
| Englewood | McMinn County | 1,617 |
| Embreeville | Unicoi County | 1,248 |
| Erin | Houston County | 1,217 |
| Eagleville | Rutherford County | 1,001 |
| Eastview | McNairy County | 768 |
| Ethridge | Lawrence County | 568 |
| Elkton | Giles County | 527 |
| Enville | Chester County | 189 |
| Elgin | Scott County | 126 |
| Essary Springs | Hardeman County | 91 |
| Eva | Benton County | 48 |