Changuinola's 2026 population is now estimated at 20,003. In 2000, the population of Changuinola was 64,773. Changuinola experienced a decrease of -1,025 residents over the past year, marking an annual decline of -4.87%. These population values and projections come from Panama census 2000 nomenclature places, Panama census 2010 nomenclature places, Panama census 2023 Cuadro 3 place population and World Population Review Internal Projections .