San Isidro's 2026 population is now estimated at 26,113. In 2000, the population of San Isidro was 43. San Isidro has grown by 1,273 in the last year, which represents a 5.12% annual change. These population values and projections come from Panama census 2000 nomenclature places, Panama census 2010 nomenclature places, Panama census 2023 Cuadro 3 place population and World Population Review Internal Projections .