Margarita's 2026 population is now estimated at 8,418. In 2000, the population of Margarita was 2,545. Margarita has grown by 294 in the last year, which represents a 3.62% annual change. These population values and projections come from Panama census 2000 nomenclature places, Panama census 2010 nomenclature places, Panama census 2023 Cuadro 3 place population and World Population Review Internal Projections .