Laws by Country
Ozone Therapy Legal Countries 2025
Country | Year Legalized↓ | Additional Details | |
|---|---|---|---|
 | Venezuela | 2020 | |
 | Mexico | 2018 | Only in one state. |
 | Brazil | 2015 | Regularized for dentistry in 2015, medicine in 2018, and veterinary care in 2020. On 7 August 2023, the Brazilian government legalized ozone therapy as a complementary therapy, ignoring a request for veto due to lack of scientific evidence made in an open letter from the Brazilian National Academy of Medicine |
 | Turkey | 2014 | |
 | Portugal | 2013 | Broadened scope in 2014. |
 | United Arab Emirates | 2011 | Only in Dubai City. |
 | Oman | 2010 | |
 | Cuba | 2009 | Broadened scope in 2015. |
 | Spain | 2007 | Legal in private centers in 15 of the 17 Spanish autonomous communities, as well as in roughly 23 Spanish hospitals. |
 | China | 2005 | |
 | Russia | 2005 | Broadened scope in 2007. |
 | Italy | 2003 | Broadened scope in 2007 and 2009. |
 | Ukraine | 2001 | Broadened scope in 2014. |
 | Greece | 1991 | Greece was the first country to regularize ozone therapy, doing so on 1991 for vascular surgery and broadening the scope in 2014 to include all specialties and diseases, both in the public and private sectors. |
Currently, there are 14 countries where ozone therapy has been regularized, either throughout the country or in some parts of it.
However, the undertaking isn’t considered a viable treatment option by certain government-regulating agencies, including the U.S. Food and Drug Administration (FDA), which prohibits the application of ozone therapy.
Ozone Therapy and the Controversies Surrounding It
As medical researchers persistently strive to identify various methods for treating ailments, such efforts can often be unusual and controversial—ozone therapy being an example.
The ozone substance is a variation of the standard oxygen gas, which people breathe to survive. It was discovered in 1785 by Dutch physicist Martin van Marum (1750-1837) and manufactured in May 1840 by the German chemist Christian Friedrich Schönbein (1799-1868).
Ozone is said to be dangerous when inhaled. This gas is known to cause respiratory symptoms such as wheezing, coughing, irritated lung lining, sore throat, and permanent lung damage, especially after excessive exposure.
The FDA prohibits ozone therapy on the basis that it’s a potentially harmful substance, and further research is needed before the medical community can safely declare it an acceptable treatment option.
Regardless of these concerns, certain aspects of the scientific community maintain that ozone can provide hypothetically significant health benefits when administered through alternative methods. Such methods include direct tissue entry, intramuscularly, and intravenously.
Therapeutic researchers suggest that ozone therapy is relatively safe and effective in remediating ailments like cardiovascular problems, lung conditions, wounds, liver issues, and cancer.
Ozone Therapy Legal Countries
Here’s a list of the 14 countries where ozone therapy has been regularized so far. The list starts with the first country in the world to regularize ozone therapy to the most recent one.
- Greece (1991 and 2014)
- Ukraine (2001 and 2014)
- Italy in 3 regions (2003, 2006, 2007, 2009)
- China (2005)
- Russia (2005 and 2007)
- Spain (2007 and 2012) in 15 autonomous communities
- Cuba (2009 and 2015)
- Sultanate of Oman (2010)
- United Arab Emirates (UAE) in Dubai (2011)
- Portugal (2013 and 2014)
- Turkey (2014)
- Brazil in dentistry (2015) and medicine in the public sector (2018)
- Mexico (2018)
- Venezuela (2020)
History has it that it’s been difficult for ozone therapy to have a substantial manifestation on the global medical agendas. However, the gradual rising use of ozone therapy, mainly in Germany and the former Soviet Union from the 1960s, has provoked renewed interest in the controlled use of ozone therapy following adopted protocols.
Ozone therapy has been emerging in various European states, mainly in Italy, Spain, and Cuba, where it’s reinforced by the world’s only research foundation in the medical ozone therapy. China became another state where the treatment has had some importance after its introduction in 2000.
Today we can definitely say that the use of ozone therapy is increasing in different countries as the analysis for its regularization is still ongoing. The number of ozone therapists exceeds 30 000, where Germany leads with 11,000 practitioners, China is next with 5,000, and Russia comes third with 3,500 professionals.
