| City | County | 2026 Pop. ↓ |
|---|---|---|
| Davie | Broward County | 111,993 |
| Deltona | Volusia County | 101,760 |
| Daytona Beach | Volusia County | 91,916 |
| Deerfield Beach | Broward County | 90,018 |
| Doral | Miami-Dade County | 83,243 |
| Delray Beach | Palm Beach County | 70,560 |
| DeLand | Volusia County | 48,158 |
| Dunedin | Pinellas County | 35,140 |
| Dania Beach | Broward County | 33,028 |
| DeBary | Volusia County | 23,827 |
| Davenport | Polk County | 19,859 |
| Destin | Okaloosa County | 14,051 |
| Doctor Phillips | Orange County | 12,799 |
| Dade City | Pasco County | 10,767 |
| DeFuniak Springs | Walton County | 7,620 |
| Dundee | Polk County | 6,676 |
| Daytona Beach Shores | Volusia County | 5,207 |
| Dade City North | Hernando County | 3,034 |
| Dover | Hillsborough County | 3,031 |
| De Leon Springs | Volusia County | 2,823 |
| Dunnellon | Citrus County | 2,081 |
| Desoto Lakes | Sarasota County | 1,858 |
| DeLand Southwest | Lake County | 1,040 |
| Desoto Acres | Sarasota County | 948 |
| Duck Key | Monroe County | 786 |
| Day | Lafayette County | 219 |
| Dickerson City | Santa Rosa County | 57 |
| Dixonville | Santa Rosa County | 11 |