| City | County | 2026 Pop. ↓ |
|---|---|---|
| Ellsworth | Hancock County | 8,874 |
| Eliot | York County | 7,805 |
| Eddington | Penobscot County | 2,250 |
| East Millinocket | Penobscot County | 1,562 |
| Enfield | Penobscot County | 1,441 |
| East Machias | Washington County | 1,340 |
| Easton | Aroostook County | 1,304 |
| Eastport | Washington County | 1,280 |
| Etna | Penobscot County | 1,246 |
| Edgecomb | Lincoln County | 1,213 |
| Exeter | Penobscot County | 1,007 |
| Embden | Somerset County | 962 |
| Eagle Lake | Aroostook County | 749 |
| Eustis | Franklin County | 671 |
| Eastbrook | Hancock County | 431 |
| Edinburg | Penobscot County | 136 |