16 cities
| City | County | 2026 Pop. ↓ |
|---|---|---|
| Ellsworth | Hancock County | 8,946 |
| Eliot | York County | 7,689 |
| Eddington | Penobscot County | 2,276 |
| East Millinocket | Penobscot County | 1,560 |
| Enfield | Penobscot County | 1,441 |
| East Machias | Washington County | 1,321 |
| Easton | Aroostook County | 1,308 |
| Eastport | Washington County | 1,284 |
| Etna | Penobscot County | 1,236 |
| Edgecomb | Lincoln County | 1,213 |
| Exeter | Penobscot County | 1,000 |
| Embden | Somerset County | 972 |
| Eagle Lake | Aroostook County | 746 |
| Eustis | Franklin County | 686 |
| Eastbrook | Hancock County | 428 |
| Edinburg | Penobscot County | 133 |