16 cities
| City | County | 2025 Pop. ↓ |
|---|---|---|
| Ellsworth | Hancock County | 8,719 |
| Eliot | York County | 7,631 |
| Eddington | Penobscot County | 2,257 |
| East Millinocket | Penobscot County | 1,562 |
| Enfield | Penobscot County | 1,439 |
| East Machias | Washington County | 1,347 |
| Easton | Aroostook County | 1,324 |
| Eastport | Washington County | 1,296 |
| Etna | Penobscot County | 1,236 |
| Edgecomb | Lincoln County | 1,230 |
| Exeter | Penobscot County | 998 |
| Embden | Somerset County | 970 |
| Eagle Lake | Aroostook County | 764 |
| Eustis | Franklin County | 672 |
| Eastbrook | Hancock County | 429 |
| Edinburg | Penobscot County | 135 |