8 cities
| City | County | 2026 Pop. ↓ |
|---|---|---|
| Olive Branch | DeSoto County | 47,766 |
| Oxford | Lafayette County | 27,448 |
| Ocean Springs | Jackson County | 19,246 |
| Oak Grove | Covington County | 2,708 |
| Okolona | Chickasaw County | 2,372 |
| Oakland | Yalobusha County | 456 |
| Osyka | Pike County | 353 |
| Ovett | Jones County | 198 |