Mendefera's 2026 population is now estimated at 64,315. In 1984, the population of Mendefera was 12,184. Mendefera has grown by 2,497 in the last year, which represents a 4.04% annual change. These population values and projections come from Eritrea citypopulation fallback - census 1984 city counts, Eritrea citypopulation fallback - estimate 1997 city counts and World Population Review Internal Projections .
| City | 2026 Pop. ↓ | Growth |
|---|---|---|
| Asmara | 783,135 | 2.52% |
| Keren | 236,969 | 5.13% |
| Assab | 97,402 | 2.76% |
| Massawa | 95,938 | 4.45% |
| Agordat | 95,136 | 5.13% |
| Dekemhare | 92,403 | 5.13% |
| Ghinda | 66,245 | 5.13% |
| Tessenei | 65,341 | 5.13% |
| Mendefera | 64,315 | 4.04% |
| Adi Qayeh | 57,913 | 4.62% |
| Barentu | 56,354 | 5.13% |
| Senafe | 52,360 | 5.13% |
| Afabet | 35,673 | 0% |
| Segeneiti | 24,141 | 4.83% |
| Adi Qala | 21,136 | 3.77% |
| Hagaz | 11,861 | 0% |
| Adi Tekelezan | 9,616 | 0% |
| Golluj | 9,297 | 0% |
| Umhajer | 9,240 | 0% |
| Areza | 4,774 | 0% |
| Nacfa | 4,312 | 0% |
| Tserona | 3,557 | 0% |
| Debarwa | 3,435 | 0% |
| Haykota | 2,587 | 0% |
