City | 2024 Population |
|---|---|
| Sagamore | 4,140 |
| Salem | 45,094 |
| Salisbury | 5,422 |
| Sandisfield | 978 |
| Sandwich | 2,968 |
| Saugus | 28,656 |
| Savoy | 642 |
| Scituate | 4,986 |
| Seabrook | 573 |
| Seconsett Island | 231 |
| Seekonk | 15,701 |
| Sharon | 5,749 |
| Sheffield | 3,325 |
| Shelburne | 1,882 |
| Shelburne Falls | 1,729 |
| Sherborn | 4,338 |
| Shirley | 1,002 |
| Shrewsbury | 41,239 |
| Shutesbury | 1,724 |
| Siasconset | 141 |
| Smith Mills | 4,406 |
| Somerset | 18,256 |
| Somerville | 80,249 |
| South Ashburnham | 1,215 |
| South Deerfield | 1,756 |
| South Dennis | 3,307 |
| South Duxbury | 3,465 |
| South Hadley | 17,824 |
| South Lancaster | 1,686 |
| South Yarmouth | 12,023 |
| Southampton | 6,183 |
| Southborough | 10,335 |
| Southbridge Town | 17,940 |
| Southwick | 9,150 |
| Spencer | 5,464 |
| Springfield | 153,136 |
| Sterling | 8,083 |
| Stockbridge | 1,972 |
| Stoneham | 22,822 |
| Stoughton | 28,643 |
| Stow | 6,994 |
| Sturbridge | 2,232 |
| Sudbury | 18,773 |
| Sunderland | 3,625 |
| Sutton | 9,365 |
| Swampscott | 15,066 |
| Swansea | 17,311 |