| City | County | 2025 Pop. ↓ |
|---|---|---|
| D'Iberville | Harrison County | 13,667 |
| Diamondhead | Hancock County | 9,055 |
| Decatur | Newton County | 1,906 |
| Durant | Holmes County | 1,890 |
| DeLisle | Hancock County | 1,692 |
| Drew | Sunflower County | 1,618 |
| Duck Hill | Montgomery County | 1,531 |
| Derma | Calhoun County | 887 |
| De Kalb | Kemper County | 811 |
| Dumas | Tippah County | 449 |
| D'Lo | Rankin County | 359 |
| De Soto | Clarke County | 341 |
| Duncan | Bolivar County | 265 |
| Darling | Quitman County | 140 |
| Doddsville | Sunflower County | 65 |
| Dundee | Tunica County | 56 |
| Dennis | Tishomingo County | 26 |